Review
Sep 2026
A mini-review of the molecular mechanisms, mutational landscape, and therapeutic opportunities of TWIST1 in oncology.
TWIST1 is a deeply conserved basic helix-loop-helix (bHLH) transcription factor that has emerged as a central transcriptional regulator bridging developmental biology and cancer pathogenesis. This key regulator orchestrates mesoderm formation, neural crest migration, and craniofacial morphogenesis through precise dimer...
B. R. Pires, G. Ferreira, Eliana Abdelhay
· Biochimica et biophysica act... · 0 citations