340. Synaptic density in psychiatric and neurodegenerative disorders: a systematic review of in vivo SV2A PET studies
Abstract Background Over four decades of research have linked synaptic pathology to a broad range of brain disorders. Postmortem studies in conditions like psychosis spectrum disorders, Parkinson’s and Alzheimer’s Disease (AD) show changes in synaptic integrity but are confounded by factors such as illness duration or...