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Author

G. Gervasini

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2 papers indexed here

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Open access Sep 2026

Phenotype-Specific Pharmacogenetic Patterns of Methotrexate Neurotoxicity in Pediatric Acute Lymphoblastic Leukemia

Background: Methotrexate-induced neurotoxicity (MTX-NTX) is a severe complication during childhood acute lymphoblastic leukemia (ALL) treatment, yet its underlying pharmacogenetic determinants remain incompletely understood. Methods: A multicenter retrospective nationwide case–control study was performed including 71 p...

Javier Gómez-Román, Juan Restrepo, L. M. González et al. · 0 citations
Review Open access Sep 2026

Genetic Basis of Tobacco Use Disorder

This review summarizes the current evidence on the genetic basis of TUD and discusses the limitations of early candidate-gene studies and the paradigm shift introduced by large GWAS and meta-analyses, and polygenic risk scores, which indicate that tobacco use and nicotine dependence have a highly polygenic and pleiotro...

G. Gervasini · 0 citations

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