We assessed the cost-effectiveness of a publicly funded lifestyle programme (supervised exercise and nutritional counselling) for adults with obesity (BMI 30.0–34.9 kg/m
2
) in Southern Italy and its projected effect on colorectal and hepatocellular cancer burden. A deterministic cohort state-transition (Markov-typ...
M. Polignano, Davide Guido, O. Rotolo et al.· Frontiers in Public Health· 0 citations
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide. Its prevalence is constantly increasing, particularly among obese individuals. Lifestyle modifications remain the first-line intervention for the management and treatment of MASLD. The most w...
R. Tatoli, Rossella Donghia, P. L. Pesole et al.· Nutrients· 0 citations
Background & aims. Plant-based dietary patterns, such as the Mediterranean diet, are considered protective against MASLD. The Mediterranean diet is rich in polyphenols (PP), plant-derived metabolites that exhibit anti-fibrotic effects in experimental models. This study aimed to evaluate the association between dietary...
C. Bonfiglio, M. N. Pastore, Manuela Siani et al.· Nutrients· 0 citations
Evidence on stromal biomarkers with prognostic or predictive value, including tumor–stroma ratio, fibrosis burden, cancer-associated fibroblast states, extracellular matrix stiffness, vascular accessibility, and spatial immune features are summarized.
M. De Luca, Francesco Balestra, Giorgia Panzetta et al.· Cells· 0 citations
AMIUGraph provides a clinically grounded and utility-driven benchmarking framework that jointly evaluates KGE and GNN models across multiple healthcare graph types and learning settings, and offers practical guidance for selecting graph-based models in medical decision-support systems.
P. Sorino, A. D. Bellis, Daniele Malitesta et al.· BMC Medical Informatics and...· 0 citations
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