Author

G. Hudjashov

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Open access Aug 2026

ADVANCING GENOTYPE IMPUTATION IN ANCIENT GENOMES USING A REGION-SPECIFIC REFERENCE PANEL AND BENCHMARK GENOTYPES

Background Ancient DNA datasets are often characterized by low coverage and high levels of missing data, which limit the use of diploid-based analyses and constrain population genetic inference. Although genotype imputation is increasingly used to overcome these limitations, its performance depends strongly on the comp...

Erkin Alaçamlı, Stefania Sasso, Roberto Didonna et al. · bioRxiv · 0 citations

Open access Jul 2026

Psychiatric genetic liability is associated with the severity of COVID-19 and other acute respiratory infections: an observational study across five Northern European countries

The results underscore the role of psychiatric genetic liability, beyond diagnosed psychiatric disorders, in contributing to both COVID-19 and other respiratory infection severity, and provide insights that may improve future risk stratification and public health strategies targeting respiratory viruses.

K. Kõiv, R. Askeland, L. N. Christoffersen et al. · Genome Medicine · 0 citations

Open access Aug 2026

Detecting CYP2C19 deletions from genotyping array signals using neural networks

This work developed a neural network model, nnCNV, to predict deletions in the CYP2C19 pharmacogene region from array intensity signals and demonstrated that long-range information, which cannot be utilized by hidden Markov models, can improve CNV calling.

Burak Yelmen, R. Hofmeister, Viido Kaur Lutsar et al. · bioRxiv · 0 citations