Clinical and immunological markers of transformation of an acute demyelinating episode to a chronic demyelinating disease
An acute demyelinating episode (ADE) is the acute onset of clinical symptoms characteristic of multiple sclerosis (MS) or other demyelinating diseases (DD). Patients with ADE may experience either a monophasic course of the disease, relapses, or transformation to MS (up to 33 per cent). To date, there are no criteria f...