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G. Jour

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Open access Sep 2026

Genotype-driven tumor ecosystems drive immune evasion and immunotherapy resistance in melanoma

This study links an understudied melanoma driver to specific immune-evasion mechanisms and identifies EGFR inhibition as a candidate strategy to improve outcomes in patients with NF1-mutant melanoma resistant to immunotherapy.

Milad Ibrahim, Irineu Illa-Bochaca, T. Muijlwijk et al. · 0 citations
Review Aug 2026

Histopathology and Clinical Features of SPARK Nevi in a Multi-Institutional Cohort.

This largest series defines the clinicopathologic and immunohistochemical spectrum of SPARK-pattern lesions and demonstrates overall benign behavior despite morphologic overlap with dysplastic nevus and melanoma.

D. El-Rayes, Albatool AlMahdy, Gerardo Cazzato et al. · 0 citations
Review Sep 2026

Genome Profiling of Actionable Cancer Targets (NYU LG-PACT) for Clinical Patient Molecular Diagnostics and Treatment

The technical challenges of validating an NGS oncological diagnostic targeted assay for clinical grade accuracy and sensitivity for patient care are presented and how copy number alterations provide a more comprehensive description of the tumors genomic profile are shown.

Y. Yang, V. Vasudevaraja, J. Serrano et al. · 0 citations

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