Doxorubicin-induced cardiotoxicity (DIC) remains a major limitation of anthracycline-based chemotherapy, characterized by progressive myocardial dysfunction and heart failure. Increasing evidence implicates microRNAs (miRNAs) as critical post-transcriptional regulators of cardiomyocyte survival; however, their pharmaco...
I. S. Dhami, Satinder Kaur, G. K. Bhatti et al.· European Journal of Pharmaco...· 0 citations
BACKGROUND
The Asia Pacific region is home to more than half of the world's 1·93 billion adolescents (aged 10-24 years). Addressing adolescent health in this region is of global importance, but to date a systematic analysis of key contributors to disease in adolescents has not been done, which is a barrier to responsiv...
K. Cini, Dorothea Dumuid, Iffat Abbsar et al.· The Lancet Child & Adolescen...· 0 citations
A mechanistic view on the use of multi‐omics strategies for the investigation of NATs‐induced biological effects to analyze the mechanism of action of chemically modified ASOs, siRNAs and mRNA conjugates is offered.
G. K. Bhatti, Anushka Verma, K. Devi et al.· Chemical Biology and Drug De...· 0 citations
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