Doxorubicin-induced cardiotoxicity (DIC) remains a major limitation of anthracycline-based chemotherapy, characterized by progressive myocardial dysfunction and heart failure. Increasing evidence implicates microRNAs (miRNAs) as critical post-transcriptional regulators of cardiomyocyte survival; however, their pharmaco...
I. S. Dhami, Satinder Kaur, G. K. Bhatti et al.· European Journal of Pharmaco...· 0 citations
This systematic analysis of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2023 aims to provide a comprehensive assessment of adolescent health across the Asia Pacific region, at both the subregional and national levels, encompassing burden of disease, mortality, and prevalence of adolescent risk...
K. Cini, Dorothea Dumuid, Iffat Abbsar et al.· The Lancet Child & Adolescen...· 2 citations
A mechanistic view on the use of multi‐omics strategies for the investigation of NATs‐induced biological effects to analyze the mechanism of action of chemically modified ASOs, siRNAs and mRNA conjugates is offered.
G. K. Bhatti, Anushka Verma, K. Devi et al.· Chemical Biology and Drug De...· 0 citations
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