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Open access Aug 2026

AQbD-Guided Stability-Indicating UHPLC Method for Simultaneous Determination of Major Withanolides in Ashwagandha Root Extract and Commercial Capsules

A rapid, stability-indicating, and environmentally considerate ultra-high-performance liquid chromatographic (UHPLC) method was developed for simultaneous determination of withanoside IV, withanoside V, withaferin A, 12-deoxywithastramonolide, withanolide A, and withanolide B in Ashwagandha root extract and commercial...

G. Kiran, A. Samala, N. Raghunandan et al. · 0 citations
Open access Aug 2026

AQbD-Optimised Stability-Indicating Green RP-HPLC Method for Simultaneous Determination of Adapalene and Benzoyl Peroxide in Topical Gel

A tetrahydrofuran-free, stability-indicating reversed-phase HPLC method was developed for simultaneous determination of adapalene and benzoyl peroxide in a commercial topical gel. Analytical Quality by Design (AQbD) was used to define the analytical target profile, identify high-risk chromatographic variables, and eval...

A. Samala, G. Kiran, N. Raghunandan et al. · 0 citations

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