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G. Kopeina

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Open access Aug 2026

Cell death-based treatment of ovarian cancer

Ovarian cancer (OC) is the seventh most prevalent type of cancer in women and one of the most lethal gynecological malignancies, due to the poor prognosis (with a 5-year survival rate of about 50%), the lack of specific clinical symptoms, the absence of effective screening, and the fact that the tumor grows without o...

Aygun R. Mamedova, G. Kopeina, B. Zhivotovsky et al. · 0 citations
Open access Aug 2026

SIRT3 determines the sensitivity of cancer cells to mitochondrial targeting

The data demonstrate that SIRT3 does not play a major role in cancer cell death induced by the conventional chemotherapeutic drug cisplatin but exerts a protective role in the case of the mitochondria-targeting agent α-TOS.

M. A. Yapryntseva, Matvey A. Vinogradov, P. I. Volik et al. · 0 citations

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