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Open access Aug 2026

Distal-less homeobox 5 gives rise to myofibroblastic carcinoma-associated fibroblasts to promote collective breast cancer invasion

Tumor-promoting myofibroblastic carcinoma-associated fibroblasts (myCAFs) are induced by activation of transforming growth factor-β (TGF-β) signaling. However, the molecular basis of myCAF-specific transcriptional programs regulated by TGF-β signaling remains poorly understood. Using a meta-analysis of single-cell RNA-...

Yoshihiro Mezawa, Kohei Kumegawa, Katsuki Morita et al. · 0 citations

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