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Author

G. Labadié

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2 papers indexed here

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Open access Sep 2026

Second-generation N,N′-disubstituted aliphatic diamines: discovery of potent hits for multi-species leishmaniasis treatment

Kinetoplastid diseases remain a major global health challenge, highlighting the need for new antiparasitic chemotypes. N,N′ -disubstituted aliphatic diamines have emerged as a promising scaffold against trypanosomatid parasites. Building on our previous studies, we expanded the structure–activity relationship (SAR)...

Alejandro I. Recio-Balsells, Esteban A. Panozzo-Zénere, E. Coser et al. · 0 citations
Open access Jul 2026

Functional Mapping of the Trypanosoma cruzi Serinome by Fluorophosphonate Activity-Based Protein Profiling

An activity-based chemoproteomic map of the T. cruzi epimastigote serinome is reported by combining genome-informed in silico curation with whole-cell activity-based protein profiling (ABPP) using a panel of cell-permeable fluorophosphonate (FP)-alkyne probes to establish a fluorophosphonate-based chemoproteomic resour...

Jaime A. Isern, M. G. Mediavilla, Exequiel O. J. Porta et al. · 0 citations

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