Open access
Aug 2026
Generation and characterization of an isogenic gene-corrected iPSC line CARIMi009-A-1 from a Hutchinson-Gilford Progeria Syndrome (HGPS) patient with a heterozygous G608G mutation in the LMNA gene.
This work generated and characterized the induced isogenic pluripotency stem cell control line generated by correcting the c.1824C > T mutation and excluded differences in genetic background while studying the pathophysiology of HGPS.
G. Lezzoche, Evangelia Ntotsia, S. Seyen et al.
· Stem Cell Research · 0 citations