BACKGROUND
Elevated inflammatory biomarkers have been consistently associated with a subset of depressive symptoms, particularly atypical and energy-related features, as well as antidepressant treatment resistance. This evidence has supported the definition of an inflammatory subtype of major depressive disorder (ISMDD...
B. Vai, T. Cazzella, C. Monopoli et al.· Brain, behavior, and immunit...· 1 citation
Abstract Background Obesity and depression are highly prevalent conditions significantly impacting global health; in England alone, 25% of adults are reported to have obesity and 20% depression. With this, the high comorbidity is unsurprising, contributing to a vicious cycle between the two conditions. In parallel, the...
M. Kose, A. McLaughlin, N. Mariani et al.· International Journal of Neu...· 0 citations
Abstract Background Major depressive disorder (MDD) is highly prevalent in individuals with obesity, with both conditions occurring more frequently in females than males; however, the mechanisms underlying these sex differences remain poorly understood. Immune system hyperactivation has been proposed as a shared biolog...
G. Lombardo, A. McLaughlin, E. Lambert et al.· International Journal of Neu...· 0 citations
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