Open access
Sep 2026
PD-1 deficiency reshapes the TCRβ repertoire and T-cell developmental programs associated with susceptibility to lupus-like autoimmunity
The findings suggest that PD-1 deficiency is linked to disrupted TCRβ repertoire organization, extensive immune dysregulation, and an increased vulnerability to infection-induced lupus-like autoimmunity.
Xian-Liang Hou, Zhen-Yu Liu, G. Lu et al.
· Frontiers in Immunology · 0 citations