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Review Open access Aug 2026

KRAS-driven cytokine–metabolic crosstalk shapes immune exclusion in pancreatic ductal adenocarcinoma

This review summarizes recent evidence on KRAS-driven cytokine–metabolic crosstalk in PDAC and discusses how this genotype-associated regulatory pattern governs immune exclusion, offering novel insights into overcoming immunotherapy resistance.

Cheng-Lin Huang, G. Mai, Yu Li et al. · 0 citations

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