Cancer cells must deal with excessive reactive oxygen species (ROS) to survive severe hypoxia and anticancer therapy; however, anti-ROS mechanisms other than the well-known NFE2L2/NRF2 signaling pathway are poorly recognized. Here, we report a ROS scavenging mechanism mediated by HIF1α-KLF4-induced hemoglobin extraeryt...
Bo Zhang, Fei-Chang Liu, Xin-Yue Gao et al.· Signal Transduction and Targ...· 0 citations
The recent Andes virus (ANDV) outbreak on the MV Hondius cruise has raised global public health alarms due to its dangerous ability to person-to-person spread. Hantavirus infections primarily manifest as hemorrhagic fever with Eurasian renal syndrome (HFRS) and Americas hantavirus cardiopulmonary syndrome (HCPS), bot...
Yu-Fang Shi, Mauro Piacentini, A. Zumla et al.· Cell Death & Disease· 0 citations
These findings identify SERPINH1 as a marker of ECM-driven tumour aggressiveness and stromal reprogramming in breast cancer and emerges as a promising prognostic biomarker and a tractable therapeutic target in breast cancer.
M. Scimeca, V. Palumbo, F. Servadei et al.· Biology Direct· 0 citations
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