Author

G. Oduselu

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Open access Sep 2026

Schiff Base Derivatives of Benzothiazole and Benzamide as Promising Antimicrobial Agents: Integrated In Silico and In Vitro Evaluation.

Antimicrobial resistance (AMR) remains a critical global health challenge, demanding new scaffolds with potent and broad-spectrum activity. In this work, a library of Schiff-base derivatives of benzothiazoles (2a-2f) and benzamides (5a-5i) was designed, synthesised via a microwave-assisted approach, and comprehensively...

T. Ogunnupebi, G. Oduselu, O. F. Elebiju et al. · ChemMedChem · 0 citations

Open access Aug 2026

De Novo Molecular Design and Bioactivity Prediction of Novel Hexahydroquinolines as Plasmodium falciparum Calcium-Dependent Protein Kinase 4 (CDPK4) Inhibitors

Plasmodium falciparum Calcium-Dependent Protein Kinase 4 (PfCDPK4) is a validated target for malaria transmission-blocking interventions, as its inhibition disrupts male gametocyte exflagellation. Hexahydroquinolines (HHQs) have emerged as promising gametocytocidal agents. This study aimed to design novel HHQs as poten...

G. Oduselu, D. Bodun, O. Ajani et al. · Bioinformatics and Biology I... · 0 citations