Author

G. Panagiotaropoulou

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Open access Sep 2026

Population-scale immune multiome atlas reveals regulatory disease mechanisms.

Most disease-associated genetic variants lie in non-coding regions1,2, yet mechanistic insights are limited by the lack of an empirical framework for characterizing the molecular consequences of regulatory variation. Single-cell molecular quantitative trait locus (QTL) mapping3,4 connects variants to gene regulation bu...

Masahiro Kanai, T. Delorey, Jarno Honkanen et al. · Nature · 2 citations

Open access Aug 2026

Genomic dimensions deconstruct the clinical heterogeneity of bipolar disorder

Bipolar disorder’s genetic architecture appears hierarchical—a general liability resolving into dimensions of course and comorbidity, beyond subtypes, beyond subtypes.

Tracey van der Veen, M. Tesfaye, J. M. K. Yang et al. · Research Square · 0 citations

Aug 2026

Distinguishing different psychiatric disorders using DDx-PRS

Despite great progress on case–control polygenic prediction, an unmet need remains for a method that genetically distinguishes clinically related disorders (e.g., schizophrenia (SCZ) versus bipolar disorder (BIP) versus major depressive disorder (MDD) versus controls). We introduce differential diagnosis–polygenic risk...

W. Peyrot, G. Panagiotaropoulou, L. O. Olde Loohuis et al. · Nature Genetics · 0 citations