Open access
Sep 2026
Meiotic kinetochore reconstitution identifies chromosome segregation factors
Kinetochores are complex protein assemblies at centromeres that direct and regulate chromosome segregation1. During gamete formation by meiosis, kinetochore specialisations drive two sequential and distinct segregation events to partition half the genome to the offspring2,3. Age-dependent segregation errors in human oo...
G. Pieper, Niamh O'Loughlin, M. Aboelenain et al.
· bioRxiv · 0 citations