Introduction Myelin water imaging provides a non-invasive approach for indirectly investigating myelin content of the brain by magnetic resonance Imaging (MRI). Myelin water fraction (MWF) reflects the fraction of water signal associated with water trapped between myelin layers. Postmortem imaging provides a unique opp...
L. Sanches, Narges Taghizadehsalehabad, R. Moqadam et al.· bioRxiv· 0 citations
PURPOSE
To develop and validate a repeatable and reproducible approach, QuantoRAGE, for simultaneous whole-brain T1 and T2 mapping using adiabatic magnetization preparation.
METHODS
QuantoRAGE is a 3D FLASH-based sequence using an adiabatic T2-prepared inversion followed by two readout blocks. Sequence repetitions wi...
Natalia Pato Montemayor, Tâm Johan Nguyên, J. Marques et al.· Magnetic Resonance in Medici...· 0 citations
Quantitative magnetic resonance imaging (qMRI) supports both basic neuroscience and clinical research, providing the foundation for longitudinal studies of brain development, aging, and neurological disease. However, its validity rests on a little-studied assumption: that physical relocation of imaging hardware leaves...
S. Tambalo, A. Finora, P. A. Maldonado Moscoso et al.· medRxiv· 0 citations
Quantitative T1 mapping (qT1) is a magnetic resonance imaging (MRI) biomarker of brain microstructural changes; however, its application in Alzheimer disease (AD) remains limited. We compared cortico-limbic qT1 values between patients with AD and healthy controls (HCs) and examined their relationship with amyloid burde...
L. Gualco, N. Montobbio, M. Losa et al.· European Radiology Experimen...· 0 citations
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