Author

G. Randolph

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Open access Oct 2026

APOE4 reduction in vascular-associated fibroblasts decreases cerebral amyloid angiopathy and associated vascular dysfunction

Vascular-associated fibroblasts are a major source of pathogenic APOE4 that drives vascular dysfunction in cerebral amyloid angiopathy and are establish VAF-derived APOE4 as a compartment-specific driver of CAA and cerebrovascular dysfunction.

Fareeha Saadi, Yoonho Cho, Ilia V. Katritch et al. · bioRxiv · 0 citations

Open access Aug 2026

Functional role of skull lymphoid structures in CNS immunosurveillance

Functional lymphoid structures within the skull bone marrow enable central nervous system immunosurveillance and shape immune responses to brain disease.

J. Park, D. Abramishvili, G. Davanzo et al. · Nature · 4 citations