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Author

G. Rocchitta

2 papers indexed here

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Open access Sep 2026

10d, a Pyridoquinoxaline-Based P-Glycoprotein Inhibitor, Exacerbates MPTP-Induced Neurotoxicity in PC12 Cells

Efflux pumps are essential components of cellular detoxification mechanisms, regulating the intracellular accumulation of xenobiotics and endogenous compounds. Among them, P-glycoprotein (P-gp) plays a role in protecting the brain from potentially toxic molecules, and alterations in its function have been associated wi...

Claudia Cannas, G. Rocchitta, Antonio Carta et al. · 0 citations
Open access Sep 2026

Valorization of Sardinian Grapevine Leaves as a Sustainable Source of Flavonols with Anticancer Potential

Grapevine (Vitis vinifera L.) leaves are an abundant agricultural by-product and an underexploited source of bioactive polyphenols. This study characterized hydroalcoholic leaf extracts from autochthonous Sardinian cultivars and evaluated their effects in RKO human colorectal carcinoma cells. LC–HRMS revealed flavonol-...

Ylenia Spissu, M. Tomasi, C. Cossu et al. · 0 citations

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