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Author

G. Savarese

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Open access Sep 2026

The 2026 ESC heart failure guidelines: advancing science while facilitating clinical implementation

The 2026 European Society of Cardiology (ESC) guidelines for the management of heart failure introduce a series of important changes intended to simplify classification, accelerate implementation of effective therapies, and shift care toward earlier prevention and intervention. Among the most notable changes are the in...

M. Fu, G. Savarese, Karl Swedberg · 0 citations
Review Oct 2026

"Baseline Characteristics and Utilization of Medical Therapies in Acute Hospitalized and Chronic Heart Failure Patients Enrolled in GRASP-HF: Differences Between ICARe-HF and Non-ICARe-HF Centres".

BACKGROUND The Global Registries and Surveys Programme-Heart Failure (GRASP-HF) is a prospective, multicentre, international observational study assessing implementation of the 2021/2023 ESC-HF-Guidelines. GRASP-HF is aligned with the Improving Care through Accreditation and Recognition in Heart Failure (ICARe-HF) prog...

O. Chioncel, G. Savarese, Cécile Laroche et al. · 0 citations
Open access Aug 2026

A Retrospective, Observational Study of Adherence, Persistence and Clinical Outcomes with Perindopril-Based Single-Pill or Free-Pill Antihypertensive Treatments in Italy.

INTRODUCTION Poor adherence limits the effectiveness of pharmacological treatments. Single-pill combinations (SPCs) improve adherence in short-term observational studies, but whether advantages are sustained long term and translate into clinical benefits remains uncertain. We evaluated long-term improvements in adheren...

A. Vintila, S. Masi, L. Degli Esposti et al. · 0 citations
Open access Sep 2026

Persistent C-reactive protein elevation and incident heart failure in adults at increased cardiovascular risk: A multinational electronic health record study.

In this selected cohort of adults at increased CV risk, persistent CRP elevation was associated with higher risk of incident HF and all-cause mortality and may suggest the prognostic relevance of elevated CRP and warrant further study of inflammation in HF development.

M. Busti, L. Monzo, T. Rastogi et al. · 1 citation
Oct 2026

Pharmacological treatment strategies to prevent heart failure across the cardiovascular-kidney-metabolic spectrum: an EJHF Expert Consensus Statement.

Heart failure (HF) remains a major cause of morbidity, mortality, and increased healthcare costs worldwide, and is recognized as the result of progressive cardiovascular-kidney-metabolic (CKM) syndrome. Obesity, type 2 diabetes, chronic kidney disease, hypertension, and atherosclerotic cardiovascular disease frequently...

R. Inciardi, A. Abdin, M. Abdelhamid et al. · 0 citations
Open access Sep 2026

New Evidence in Heart Failure: 2026 Update.

Therapeutic developments continue to reshape HF management across the spectrum of left ventricular ejection fraction, and support the transition from a predominantly phenotype-based approach towards a more personalized and biologically informed model of HF care.

Valentino Liguori, Angelica Rizzello, M. Adamo et al. · 0 citations

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