Pretreatment Cachexia Index Is Associated With Severe Treatment Toxicity and Overall Survival in HPV-Negative Head and Neck Squamous Cell Carcinoma.
INTRODUCTION Cancer cachexia is characterized by skeletal muscle loss, poor nutrition, and systemic inflammation and is common in head and neck cancer. We evaluated whether the Cachexia Index (CXI) predicts treatment toxicity and survival in HPV-negative HNSCC. METHODS This study included 353 patients undergoing cura...