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Author

G. Sieck

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Open access Jul 2026

Molecular Mechanisms Underlying FCCP-Induced Mitophagy in Human Airway Smooth Muscle Cells

It is hypothesized that FCCP-induced mitochondrial depolarization activates the PINK1-Parkin-mediated mitophagy pathway, culminating in the clearance of damaged mitochondria, and these findings demonstrate that FCCP robustly activates the canonical PINK1-Parkin mitophagy pathway in hASM cells.

Sanjana Mahadev Bhat, Oscar A. Ramirez Ramirez, G. Sieck · 0 citations

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