Author

G. Silva

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Open access Oct 2026

Intensive blood-pressure control for the prevention of major cardiovascular events in stroke patients: rationale and design of the OPTIMAL-STROKE trial

Abstract Background In high cardiovascular risk populations without prior stroke, intensive blood pressure (BP) lowering confers greater reductions in cardiovascular events than standard targets. However, optimal BP targets in patients with ischaemic stroke (IS) or TIA remain uncertain. The primary objective of the OPT...

G. Silva, M. J. Machline-Carrion, K. Santo et al. · European Stroke Journal · 0 citations

Open access Sep 2026

Stroke Burden Attributable to Risk Factors in the Americas, 1990 to 2021: A Temporal Trends Analysis From the GBD Study 2021.

BACKGROUND Stroke burden varies across the Americas, yet data on modifiable risk factor contributions remain limited. METHODS Using GBD (Global Burden of Disease) study 2021 data, we analyzed stroke mortality and disability-adjusted life-year (DALY) rates attributable to 23 modifiable risk factors across 39 countries...

Felipe Fregni, B. Almarie, Ramón Martínez et al. · Journal of the American Hear... · 0 citations

Open access Aug 2026

Seasonal and Temperature-Related Variation in Subarachnoid Hemorrhage Hospital Admissions: A Nationwide Ecological Time-Series Analysis in Brazil, 2020-2024.

BACKGROUND Subarachnoid hemorrhage (SAH) carries high mortality worldwide. Seasonal patterns have been documented in temperate regions, but evidence from tropical and subtropical populations remains limited. We investigated associations between meteorological variables and SAH hospital admissions across diverse climate...

Daniela Laranja Gomes Rodrigues, João Brainer Clares de Andrade, G. Silva · Neurocritical Care · 0 citations