Author

G. Simonetti

3 papers indexed here

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Oct 2026

[Position paper on the processing of personal data in clinical and outcomes research.]

This position paper examines the strategic value of clinical and outcome research data for the National Health Service, with a specific focus on the dual mandate of Scientific Institutes for Research, Hospitalization and Healthcare (IRCCS) and the role of Local Health Authorities as custodians of extensive Real World D...

Nicola Gentili, V. Danesi, R. Gaggeri et al. · Recenti progressi in medicin... · 0 citations

Open access Oct 2026

ZNF292 mutations impair RNA and protein biosynthesis defining an adverse prognostic subset in early-stage chronic lymphocytic leukemia

ZNF292 alterations are recurrently detected in patients with chronic lymphocytic leukemia (CLL), occurring in 3%-6% of patients as mutations and in 2% as 6q deletions. Although preliminary evidence suggested an independent prognostic role for ZNF292 mutations, their specific clinical relevance in early-stage CLL and th...

A. Rodríguez-Sánchez, María Alonso-Gago, C. Pérez-Carretero et al. · Biomarker Research · 0 citations

Open access Aug 2026

Impact of genetic polymorphisms on the response to transdermal fentanyl in cancer patients—a single-center, prospective, biological study

Background/objectives Transdermal fentanyl (TDF) is widely used for moderate-to-severe cancer pain, yet substantial variability in fentanyl exposure, analgesic response, and tolerability remains incompletely explained by clinical factors. We evaluated whether pharmacogenetic variability is associated with pharmacokinet...

Lucia Angelini, I. Azzali, A. Carlini et al. · Frontiers in Pain Research · 0 citations