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Review Open access Sep 2026

Fenofibrate in ophthalmology: therapeutic efficacy and mechanisms

Ophthalmic diseases are a growing global cause of visual impairment, driven by population aging and the rising prevalence of diabetes mellitus. Fenofibrate, a peroxisome proliferator-activated receptor alpha (PPARα) agonist widely used for dyslipidemia, has emerged as a candidate for therapeutic repurposing in ophthalm...

Sean Chung-Hei Ho, I. Lee, Chang Liu et al. · 0 citations
Open access Aug 2026

Macular Choriocapillaris and Retinal Microvascular Alterations Across the Prediabetes–Early Type 2 Diabetes Continuum

Purpose To characterize macular microvascular alterations across the dysglycemia spectrum, from prediabetes (pre-DM) to early type 2 diabetes (T2DM), before clinically detectable diabetic retinopathy develops. Methods In this cross-sectional study, participants with pre-DM, recent-onset T2DM, and age-matched healthy co...

Fang Zheng, Yueheng Hong, Jacqueline Chua et al. · 0 citations

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