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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

G. Trynka

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2 papers indexed here

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Open access Sep 2026

Single-cell multi-ancestry regulatory map of systemic lupus erythematosus

Integrating genomic and single-cell transcriptomic profiles from patient cohorts can uncover regulatory effects underlying genetic associations with disease. Here we present SLEmap, a multi-ancestry single-cell expression quantitative trait locus (sc-eQTL) map generated from peripheral blood mononuclear cells from 281...

Haerin Jang, C. Sutherland, Wanseon Lee et al. · 0 citations
Open access Jul 2026

Genetic dose-response modelling predicts drug mechanisms, dosing, and adverse events

Understanding how changes in gene function affect disease risk is central to drug development. Genetic variants are natural perturbations of gene activity and provide an opportunity to systematically model dose-response relationships between genes and phenotypes. Here, we present Variant-Informed Dose-Response Analysis...

L. Stefanucci, D. Considine, Z. Ke et al. · 0 citations

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