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Author

G. W. Miller

2 papers indexed here

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Open access Aug 2026

Discovery of Selective Small-Molecule Ligands of SV2C by AI-Enhanced Virtual Screening and Experimental Validation

Synaptic vesicle glycoprotein 2C (SV2C) is a vesicular protein enriched in dopaminergic neurons of the basal ganglia that modulates dopamine storage and release, and its disruption is implicated in Parkinson’s disease (PD). Despite strong genetic and pathological links to PD, there are no selective small-molecule probe...

Alexander C. Brueckner, Matthew F. Martin, Sheenam Khuttan et al. · 0 citations
Sep 2026

Circulating metabolomic and chemical exposomics signatures as potential biomarkers for long-term radon exposure.

Radon is a radioactive gas and a lung carcinogen, yet lacks established blood biomarkers for long-term exposure. We aimed to identify circulating metabolomic and exposomics signatures correlated with reconstructed radon-222 exposure. Metabolites and chemical exposomes were profiled using liquid and gas chromatography-h...

Vrinda Kalia, A. Rajendrakumar, Rodrigo Cruz-Nieto et al. · 0 citations

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