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Author

Gerald F. Watts

2 papers indexed here

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Review Open access Sep 2026

Current challenges in diagnosing homozygous familial hypercholesterolemia: Insights from the historical evolution of diagnostic criteria.

BACKGROUND Homozygous familial hypercholesterolemia (HoFH) is a rare disease characterized by dysfunctional low-density lipoprotein receptors (LDLR) and markedly elevated low-density lipoprotein cholesterol (LDL-C) from birth. Cumulative exposure to elevated LDL-C results in premature atherosclerotic cardiovascular dis...

Daniel Gaudet, R. Godin, R. Rosenson et al. · 0 citations
Jul 2026

Longer-Term Efficacy and Safety of Zodasiran in Patients with Mixed Hyperlipidaemia.

BACKGROUND Mixed hyperlipidaemia, characterized by elevated cholesterol and triglyceride levels, is associated with increased risk of atherosclerotic cardiovascular disease (ASCVD). Angiopoietin-like protein 3 (ANGPTL3) regulates lipid metabolism through inhibition of lipoprotein and endothelial lipases. Loss-of-functi...

Robert S. Rosenson, Daniel Gaudet, Christie M. Ballantyne et al. · 0 citations

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