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G. Williams

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Open access Aug 2026

Investigating a mineralocorticoid receptor-mediation of an ultra-short feedback loop regulating aldosterone production in humans

Background: Preclinical studies suggest a novel aldosterone regulation pathway: the mineralocorticoid receptor (MR) on the adrenal cortex is a part of an MR-mediated ultra-short feedback loop regulating aldosterone production. Activation of MR on the adrenal decreases aldosterone; blockade of the MR increases aldostero...

Y. E. Yuan, Gail K. Adler, Bernard Rosner et al. · 0 citations

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