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Review Open access Sep 2026

Comparative safety and sedation-related outcomes of fospropofol disodium versus propofol for adult sedation outside general anaesthesia induction or maintenance (including ICU and procedural sedation): a systematic review, meta-analysis and trial sequential analysis

Background. Fospropofol disodium is a water-soluble prodrug of propofol that avoids a lipid emulsion carrier. It may therefore reduce injection pain, cardiorespiratory depression and lipid exposure. In May 2021 it was approved in China (H20210017) for induction of general anaesthesia in adults. Randomised trials have s...

G. Xu, Y. Shi, Y. Wang et al. · 0 citations

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