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Gregory Υ. Η. Lip

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Open access Oct 2026

Left Atrial Appendage Closure Versus Oral Anticoagulation for Prevention of Stroke or Systemic Embolism in Patients With Atrial Fibrillation: An Updated Meta-Analysis of 7004 Patients Across Six Randomized Trials.

INTRODUCTION Left atrial appendage closure (LAAC) is an emerging alternative for stroke prevention in patients with atrial fibrillation (AF) who are unsuitable for long-term oral anticoagulants (OACs). However, its efficacy and safety relative to OACs remain uncertain. METHODS Three databases were searched up to Apri...

Aymen Ahmed, Neha Saleem Paryani, Muteia Shakoor et al. · 0 citations
Open access Sep 2026

Distinct Determinants of Hospitalisation and In-Hospital Mortality After Acute Stroke: Insights into Stroke–Heart Syndrome (SHS-PARTICLES Study)

Background/Objectives: Stroke–heart syndrome (SHS) involves myocardial injury, cardiac dysfunction, and arrhythmias after acute stroke, playing a key role in prognosis. Most evidence comes from acute ischaemic stroke (IS), while cardiac involvement after haemorrhagic stroke (HS) is less understood. Additionally, the pr...

Małgorzata Chlabicz, Magdalena Krętowska, Paweł Muszyński et al. · 0 citations
Open access Aug 2026

Safety of Antiseizure Medications During Direct Oral Anticoagulant Therapy in Epilepsy.

Importance Concomitant use of antiseizure medications (ASMs) and direct oral anticoagulants (DOACs) is common in epilepsy, but comparative safety data remain limited. Objective To compare risks of thromboembolic events, major bleeding, and all-cause mortality across commonly used ASMs in adults with epilepsy receivin...

K. Schubert, C. Ferreira-Atuesta, Arunachalam Soma et al. · 0 citations
Open access Aug 2026

Integrated management of atrial fibrillation with digital health support: a pooled analysis of individual participant data from the mAFA-II and MIRACLE-AF trials.

In this pooled analysis of individual participant data from two prospective randomized trials, ABC pathway-based integrated care was associated with improved clinical outcomes in patients with AF vs. usual care, with the observed benefit primarily driven by reductions in HF/ACS-related events rather than classical AF-s...

Gregory Υ. Η. Lip, Yang Chen, Ming-Fang Li et al. · 0 citations
Open access Aug 2026

Sex and Age Differences in Outcomes After Endovascular Thrombectomy of Patients With Acute Ischemic Stroke and Atrial Fibrillation: A Danish Nationwide Study.

Women with AF had higher odds of good functional outcome and men with AF showed higher successful reperfusion rates with advancing age, suggesting age-and sex-specific influences on EVT outcomes associated with AF.

M. Alobaida, D. Lane, J. N. Hedegaard et al. · 0 citations
Open access Jul 2026

Frailty may confound the association between MASLD and cardiovascular mortality in people with cardiometabolic risk factors.

BACKGROUND While metabolic dysfunction-associated steatotic liver disease (MASLD) has been consistently associated with increased cardiovascular risk in the general population, its association with cardiovascular disease (CVD) mortality in adults with established cardiometabolic risk factor (including obesity, hyperten...

Ruoting Wang, Wenli Li, J. Lazarus et al. · 0 citations
Open access Jul 2026

Atrial fibrillation in patients with left ventricular non-compaction: incidence and associations with stroke, heart failure, and mortality.

In this observational cohort, LVNC was associated with a high incidence of AF, and the presence of AF was associated with higher risks of stroke, heart failure, and all-cause death.

A. Askarinejad, T. Lüscher, Gregory Υ. Η. Lip · 1 citation
Open access Jul 2026

Risk-Guided Screening for Atrial Fibrillation Using Electronic Health Records

The EHR-based machine learning model, FIND-AF 2.0, identifies a high-risk subpopulation for AF diagnosis among patients at elevated risk of stroke and could enable scalable, EHR-driven, risk-guided AF screening.

R. Nadarajah, Jianhua Wu, A. Wahab et al. · 0 citations

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