CircuitATLAS: Agentic reasoning over a systems neuroscience knowledge graph for target discovery in circuitopathies
CircuitATLAS provides a framework for discovering therapeutics based not only on what is molecularly disrupted in disease, but on what can be controlled to restore circuit function, and introduces a human-governed in vivo lab-in-the-loop linking hypothesis generation to experimental iteration.
Gabriel Ocana-Santero, Marko Tvrdic
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