Author

Gabriel Roberti De Oliveira

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Open access Aug 2026

Fusion-driven oncogenic programs shape the immune landscape in translocation renal cell carcinoma

Renal cell carcinomas (RCC) comprise multiple molecularly distinct cancers but most are treated empirically with therapies designed for clear cell RCC (ccRCC), the most common subtype, due to incomplete understanding of subtype-specific biology. We analyzed single-cell transcriptomes and chromatin accessibility profile...

Prathyusha Konda, Alexandra J. Wakolbinger, Yan-Tong Cui et al. · Nature Communications · 0 citations

Jul 2026

Tertiary lymphoid structures harbour stem-like tumour-specific T cells

Tertiary lymphoid structures are reservoirs of tumour-specific T cells with stem-like progenitor features that could be leveraged by T cell immunotherapies, and are found to be reservoirs of tumour-specific T cells with stem-like progenitor features that could be leveraged by T cell immune pressure.

Alexander B. Afeyan, Adi Nagler, Chloe R. Tu et al. · Nature · 2 citations