Open access
Sep 2026
nnOPN3 mediates retinal-dependent lipofuscin accumulation and its loss sensitizes keratinocytes to blue-light-induced proteomic remodeling
Together, these data define three functions of OPN3: maintaining the basal proteome in a blue-light-independent manner, enabling the adaptive blue-light response, and enabling retinal-dependent lipofuscin formation in keratinocytes.
Maiza Cristina Von Dentz, H. C. Junqueira, Manuel Alejandro Herrera López et al.
· bioRxiv · 0 citations