AQbD-Guided Stability-Indicating RP-HPLC-DAD Method for Curcuminoids in Commercial Capsules with Targeted Dye-Adulterant Screening
A stability-indicating reversed-phase HPLC method with diode-array detection was developed for simultaneous determination of curcumin, demethoxycurcumin, and bisdemethoxycurcumin in commercial capsules, with targeted screening for metanil yellow and Sudan I. Analytical Quality by Design was applied through definition o...