Jul 2026
Abstract B096: Targeting NONO as a therapeutic strategy for metastatic castration-resistant prostate cancer (mCRPC)
A first-in-class strategy targeting the RNA-binding protein NONO using TF-Scan, a mass spectrometry–based functional proteomics platform that quantifies chromatin-associated protein networks in live cells, establishes NONO as a tractable target in mCRPC and introduces RNA molecular gluing as a novel modality to suppres...
Brian McEllin, D. Canzani, Lindsay K. Pino et al.
· Clinical Cancer Research · 0 citations