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Gail A. Robertson

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Open access Oct 2026

Forward genetics reveals a conserved CNBHD-CNBHD interface that restrains EAG channel activation to regulate sleep

KCNH voltage-gated potassium channels regulate neuronal excitability, yet how their hallmark cyclic nucleotide-binding homology domains (CNBHDs) influence channel gating to regulate behavior remains unclear. Using an unbiased forward genetic screen in Caenorhabditis elegans, we identified a gain-of-function mutation in...

Xin-Yu Huang, Sudharsan Kannan, Gail A. Robertson et al. · 0 citations

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