Gang Fang

Disruption of Protein Homeostasis by Targeting Autophagosome Formation: A Novel Anticancer Strategy Inducing Cell Death

Dysregulation of intracellular protein homeostasis is closely associated with various major diseases, particularly malignant tumors. Such disruptions may arise from altered protein synthesis, protein misfolding, and dysfunction of degradation pathways such as the ubiquitin–proteasome system (UPS) and the autophagy–...