Dexmedetomidine Mitigates Sepsis-Associated Lung Injury by Suppressing Macrophage Ferroptosis via the Nrf2/HO-1 Signaling Pathway.
BACKGROUND To investigate the protective role of dexmedetomidine (DEX) in sepsis-associated acute lung injury through the regulation of macrophage ferroptosis. METHODS In silico screening of GeneCards and FerrDb Vv3 databases was performed to identify ferroptosis-related candidate genes modulated by dexmedetomidineDE...