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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Gang Wu

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Aug 2026

Discovery and Characterization of RP04340: A Highly Potent and Orally Active Pan-KRAS PROTAC Degrader.

RP04340 potently degrades multiple KRAS mutants, without affecting HRAS, NRAS, or known CRBN neosubstrates, and exhibits robust antiproliferative activity in various cancer cell lines, representing a compelling candidate for KRAS-driven cancers.

Xiang Ji, Yue-Ning Du, Qi-Guo Zhang et al. · 0 citations

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