Genomic Classification and Oncogenic Stratification of Human Papillomavirus-Associated Malignancies
HPV-driven oncogenesis is a prolonged, multi-stage process that typically evolves over decades. Although host cell-mediated immunity resolves roughly 90% of initial basal cell infections within two years, persistent high-risk strains like HPV-16 and HPV-18 frequently bypass immune clearance. As viral DNA integrates int...