Author

Gaohua Li

2 papers indexed here

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Open access Aug 2026

CEA-targeted CAR-NK cells derived from embryonic stem cells exhibit potent anti-tumor activity against colorectal cancer

Background Carcinoembryonic antigen (CEA) is overexpressed in most colorectal cancers (CRC) and serves as a promising immunotherapeutic target. However, current immune cell therapies against CRC show limited clinical efficacy, and the lack of renewable, standardized cell sources hampers broader application. The present...

Gao-Hua Li, Ling-Ping Zhao, Jing-Zhi Shen et al. · Frontiers in Immunology · 0 citations

Open access Jul 2026

Single-cell transcriptomics-guided dynamic hydrogel delivery of artemisia argyi-derived EVs relieves ER stress and promotes diabetic wound regeneration.

Diabetic wounds are characterized by persistent inflammation, impaired angiogenesis, and delayed tissue regeneration, yet effective strategies to regulate the pathological immune microenvironment remain limited. Here, integrated single-cell transcriptomics and multi-omics analyses revealed significant enrichment of end...

Dazhuang Miao, Xiaopeng Suo, Xinqian Geng et al. · Journal of Nanobiotechnology · 0 citations