Oct 2026
Novel trans-stilbene-phytophenol conjugates as potent tubulin-targeting antiproliferative agents.
A series of novel trans-stilbene-phytophenol/phenolic acid conjugates linked through a triazole moiety were synthesized via Knoevenagel condensation and copper-catalyzed azide-alkyne cycloaddition. Among the 24 synthesized compounds 23-46, compound 24 emerged as the most potent candidate, exhibiting strong cytotoxicity...
Mitodru Misra, Satyajit Halder, Puja Bag et al.
· Bioorganic & Medicinal Chemi... · 0 citations