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#artificial intelligence Preprint Aug 2026

DPTM-DT: Dual-Pretrained Transformer Multitask Representation Learning for Drug-Target Prediction

Drug-target relation prediction supports candidate screening, drug repositioning, and mechanism analysis. Existing models often use incomplete drug or protein representations, model cross-modal interactions shallowly, or train affinity regression and interaction classification separately, although these tasks describe...

Ge Kong · 0 citations
Preprint Aug 2026

Sketch2Inspire: Structure-Sensitive Evaluation for Product Retrieval

Sketch2Inspire provides a diagnostic resource for evaluating modality contribution and supports the development of structure-aware product-retrieval protocols with independent human annotation and shows that the retrieval gain from multimodal input depends on how relevance is defined.

Ge Kong · 0 citations
Aug 2026

SCAD-DTA: spherical concept alignment with dynamic multi-modal fusion for drug-target affinity prediction.

The key idea is to stabilize multimodal interaction by jointly modeling adaptive fusion dynamics and representation geometry constraints by introducing a Dynamic Cross-Modal Attention mechanism that adaptively reweights modality contributions conditioned on sample-specific context, mitigating modality dominance.

Zhensong Wang, Weiliang Han, Ge Kong et al. · 0 citations

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