DEHP exposure induces cholesterol dysregulation and inflammatory signaling in human colonic epithelial cells: Implications for early colorectal carcinogenesis.
Di(2-ethylhexyl) phthalate (DEHP), a ubiquitous plasticizer and a classified Group 2B carcinogen, is associated with increased colorectal cancer (CRC) incidence, but its causal role and mechanisms are unclear. We investigated DEHP toxicity in human colonic epithelial cells (NCM460) using an integrated multi-omics appro...