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Author

Geng-Yan Luo

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Open access Sep 2026

Library strategies differentially shape microbial, functional, and host signals in clinical metagenomic sequencing

ABSTRACT Metagenomic next-generation sequencing (mNGS) is increasingly used in infectious disease diagnostics, yet how library preparation shapes the microbial, functional, and host signals recovered from clinical samples remains poorly defined. Here, we performed a within-sample parallel comparison of three mNGS libra...

Geng-Yan Luo, Jin Zhao, Lin-Lin Xie et al. · 0 citations
Review Open access Sep 2026

Multi-kingdom microbial diversity and interaction landscapes in mosquitoes revealed by 5,163 individual meta-transcriptomes

This study conducted a nationwide single-mosquito meta-transcriptomic survey of 5,163 mosquitoes representing 100 species across China, integrating viral discovery with marker-gene profiling of bacteria, archaea, fungi, and other eukaryotic microbes to establish a detailed view of the full-spectrum microbiome.

Qin-yu Gou, Wei-Chen Wu, Pei-Bo Shi et al. · 0 citations

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